Swiftly acquire sections as slender or thick as your application calls for, without stressing about getting rid of or distorting useful tissue samples.
Megatome can be a vibrating microtome built to segment a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform surface profile, along with nominal tissue problems and information loss.
Request a estimate or demo Uniformly part substantial tissues & sample arrays Megatome is the only real microtome that will area samples as huge as intact nonhuman primate and human organs, rendering it invaluable for fields such as neuropathology.
Working the CLI straight from a Gradle endeavor is not really now supported. A distribution has to be developed by way of gradlew :j2d-cli:distZip to create a zip file made up of anything required to operate.
SE works by using a rotational electric powered subject to disperse highly electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample devoid of damaging electrically charged buildings in the tissue. This enables two-four day clearing of intact organs,
undertaking to make an aggregated Javadoc. In this instance, javadocTask ought to be set to allJavadoc to make certain the proper documentation is designed in advance of building the docset.
Megatome can be a novel microtome that permits for high-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue hurt and information loss.
eFLASH is usually a swift tissue labeling strategy that permits for uniform megatomi.com whole-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed in the course of intact tissue volumes, whilst its modular structure permits you to upgrade and personalize individual parts.
Docset creation involves at minimal two selections: the name on the docset and the location on the Javadoc files to incorporate from the docset.
This will make a docset named Sample in The present Listing. Docset creation could be custom made with optional arguments:
Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, defending specimens for many rounds of processing.
Leverage the Obvious+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to speedily apparent and label full organs. Critical highlights and features contain:
Our novel Defend tissue preservation procedure sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.